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Recent Citations

Biological adaptations in the Arctic cervid, the reindeer (Rangifer tarandus). Lin Z, Chen L et al. Science. 2019 Jun 21;364(6446). pii: eaav6312.

Two-step activation mechanism of the ClpB disaggregase for sequential substrate threading by the main ATPase motor. Deville C, Franke K et al. Cell Rep. 2019 Jun 18;27(12):3433-3446.e4.

In situ structure and assembly of the multidrug efflux pump AcrAB-TolC. Shi X, Chen M et al. Nat Commun. 2019 Jun 14;10(1):2635.

Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Gu J, Zhang L et al. Science. 2019 Jun 14;364(6445):1068-1075.

Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus. Ilca SL, Sun X et al. Nature. 2019 Jun 13;570(7760):252-256.

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News

November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

October 22, 2018

Mac users: the 1.13.1 release candidate and recent daily builds contain a fix for Mojave (OS 10.14). These versions require OS 10.10 or later.

September 21, 2018

Mac users are advised to hold off upgrading to Mojave until we find a fix for Chimera buttons not being shown until the windows containing them are resized.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

RR Distance Maps 2gbp and 2fw0

Distance Maps and Contact Maps

RR Distance Maps creates a distance map, a generalization of a protein contact map in which residue-residue distances are shown with color gradations. The map can show the Cα-Cα distances within an individual protein chain or the averages and standard deviations for multiple related chains (as in the figure). A simple binary coloring like a standard contact map can also be obtained.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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