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Recent Citations

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Lv Z, Deng YQ et al. Science. 2020 Sep 18;369(6510):1505-1509.

A molecular pore spans the double membrane of the coronavirus replication organelle. Wolff G, Limpens RWAL et al. Science. 2020 Sep 11;369(6509):1395-1398.

Structural basis of transcription-translation coupling. Wang C, Molodtsov V et al. Science. 2020 Sep 11;369(6509):1359-1365.

Shared structural mechanisms of general anaesthetics and benzodiazepines. Kim JJ, Gharpure A et al. Nature. 2020 Sep 10;585(7824):303–308.

Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Su MY, Fromm SA et al. Nature. 2020 Sep 10;585(7824):251–255.

(Previously featured citations...)

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News

November 13, 2019

Chimera production release 1.14 is now available. See the release notes for what's new.

September 21, 2019

A production release candidate (version 1.14) is available; please try it and report any problems. See the release notes for what's new.

November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

(Previous news...)

Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. High-quality images and animations can be generated. Chimera includes complete documentation and is free of charge for academic, government, nonprofit, and personal use. Chimera development was supported by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX is the next-generation molecular visualization program from the RBVI, following UCSF Chimera. We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages. ChimeraX replaces a significant subset of Chimera features, includes several completely new features, and is under active development. Users may certainly choose to use both programs, and it is fine to have both installed.

Feature Highlight

phosphomannomutase morphing animation

Morphing

Different conformations and even different proteins can be compared by morphing from one structure to another. Users can specify the method of coordinate interpolation and how many intermediate structures should be generated. The result is displayed in Chimera's trajectory viewer, MD Movie. The morph can then be saved in coordinate form or recorded as an animation. See also: Animation Gallery

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

(More samples...)


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