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Recent Citations
Molecular architecture of coronavirus double-membrane vesicle pore complex. Huang Y, Wang T et al. Nature. 2024 Sep 5;633(8028):224–231.
FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions. Alcón P, Kaczmarczyk AP et al. Nature. 2024 Aug 29;632(8027):1165–1173.
Leptospira interrogans encodes a canonical BamA and three novel noNterm Omp85 outer membrane protein paralogs. Bettin EB, Grassmann AA et al. Sci Rep. 2024 Aug 28;14(1):19958.
Transport and inhibition mechanisms of the human noradrenaline transporter. Hu T, Yu Z et al. Nature. 2024 Aug 22;632(8026):930–937.
Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor. Saha S, Khanppnavar B et al. Cell. 2024 Aug 22;187(17):4751-4769.e25.
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August 1, 2024
Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable August 1, 3-6 pm PDT.
July 16, 2024
Chimera production release 1.18 is now available. See the release notes for details.
June 17-18, 2024
Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable June 17-18 PDT.
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
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Interactive shadows (shadows that move as structures are moved) can be enabled in the Effects dialog or with the command set shadows. Click the image to show a small molecule rotating above a rectangular plane. This simple animation was made with the Chimera command script tumble.com. Interactive shadows also work with ribbons, surfaces, and other representations.
(More features...)Gallery Sample
The image shows the structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant, Protein Data Bank entry 4s0v. The drug is shown as spheres colored by element, and the receptor as ribbons with secondary structure elements rainbow-colored from blue at the N-terminus to red at the C-terminus. (More samples...)
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