<div dir="ltr">Thank you so much Elaine!!</div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Mon, Nov 14, 2022 at 9:42 PM Elaine Meng <<a href="mailto:meng@cgl.ucsf.edu">meng@cgl.ucsf.edu</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex">Hi Prathvi,<br>
Yes, either one.  <br>
<br>
In Chimera, they are automatically calculated when you show a molecular surface.  It creates an attribute named areaSAS, as explained here:<br>
<<a href="https://www.rbvi.ucsf.edu/chimera/docs/UsersGuide/representation.html#surfaces" rel="noreferrer" target="_blank">https://www.rbvi.ucsf.edu/chimera/docs/UsersGuide/representation.html#surfaces</a>><br>
<br>
See also this previous chimera-user post on using Chimera to get a list of residue SASA values<br>
<<a href="http://www.cgl.ucsf.edu/pipermail/chimera-users/2018-June/014729.html" rel="noreferrer" target="_blank">http://www.cgl.ucsf.edu/pipermail/chimera-users/2018-June/014729.html</a>><br>
<br>
(If you use this page <<a href="https://www.rbvi.ucsf.edu/chimera/docs/feedback.html" rel="noreferrer" target="_blank">https://www.rbvi.ucsf.edu/chimera/docs/feedback.html</a>> to search chimera-users by "sasa", that was the top hit)<br>
<br>
In ChimeraX, you would use the command "measure sasa" <br>
<<a href="https://rbvi.ucsf.edu/chimerax/docs/user/commands/measure.html#sasa" rel="noreferrer" target="_blank">https://rbvi.ucsf.edu/chimerax/docs/user/commands/measure.html#sasa</a>><br>
... then save attribute "area" to file<br>
<<a href="https://rbvi.ucsf.edu/chimerax/docs/user/commands/save.html#attributes" rel="noreferrer" target="_blank">https://rbvi.ucsf.edu/chimerax/docs/user/commands/save.html#attributes</a>><br>
<br>
I hope this helps,<br>
Elaine<br>
-----<br>
Elaine C. Meng, Ph.D.                       <br>
UCSF Chimera(X) team<br>
Department of Pharmaceutical Chemistry<br>
University of California, San Francisco<br>
<br>
> On Nov 14, 2022, at 6:29 AM, Prathvi Singh via Chimera-users <<a href="mailto:chimera-users@cgl.ucsf.edu" target="_blank">chimera-users@cgl.ucsf.edu</a>> wrote:<br>
> <br>
> Hi Elaine,<br>
> Can I use chimera or chimeraX to know the solvent accessible surface area (SASA) for selected residues?<br>
<br>
</blockquote></div><br clear="all"><div><br></div>-- <br><div dir="ltr" class="gmail_signature"><div dir="ltr"><div><div dir="ltr">Prathvi Singh,<div>Research Fellow,<br><div>Department of Biological Sciences & Bioengineering,</div><div>Indian Institute of Technology, Kanpur-208016</div></div></div></div></div></div>