[Chimera-users] Question about Gaussion filtering

[Tom Goddard]

Hi Cao,

  Chimera Gaussian filtering is done by the “vop gaussian” command described in the Chimera manual

	https://www.cgl.ucsf.edu/chimera/docs/UsersGuide/midas/vop.html#gaussian <https://www.cgl.ucsf.edu/chimera/docs/UsersGuide/midas/vop.html#gaussian>

It convolves a 3d Gaussian function with a map, a very standard operation that smooths data.  It is implemented with a fast Fourier transform.  Look up “gaussian convolution” online to find more details about the math, for example,

	https://en.wikipedia.org/wiki/Gaussian_blur

  Tom


> On Dec 12, 2018, at 11:35 PM, CAO, Sheng <1155083065 at link.cuhk.edu.hk> wrote:
> 
> Dear Sir/Madam,
> 
> I am a Ph.D student from The Chinese University of Hong Kong that have just begun to learn structural biology.
> 
> I found that the Gaussion filtering in Chimera has a much better result than other programs.  And I an quite interested in it.
> 
> Could you please share the principle of the Gaussion filtering algorithm used in Chimera?
> 
> Thank you.
> 
> 
> Best Regards,
> Cao Sheng
> 
> 
> Postgraduate of The Chinese University of Hong Kong
> Major: Chemistry
> E-mail: 904323223 at qq.com <mailto:904323223 at qq.com>
> Address: G55, Science Centre South Block, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
> P.R.China
> 
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