The Blast Protein tool performs a blast or psiblast search of pdb or nr for sequences similar to a query, using a Web service hosted by the UCSF RBVI. The query can be:

• a chain from a structure open in Chimera
• a sequence pasted as plain text
• a sequence from an alignment in Multalign Viewer

• as a pseudo-multiple sequence alignment (a consolidation of the pairwise alignments of individual hits to the query), automatically shown in Multalign Viewer
• as structures (for hits from pdb), automatically superimposed according to the pseudo-multiple alignment

Thermosomes are hollow balls inside which proteins are folded. They are found in the cytosol of eukaryotes and in archaea. Eukaryotic thermosomes have 8 different protein subunits, while archaeal ones are composed of one, two or three different proteins. The one shown from Thermoplasma acidophilum has two distinct proteins colored blue and yellow, each present in 8 copies. The two proteins have 60% sequence identity and are very similar in structure. One monomer is shown as a ribbon. Actin and tubulin are folded by eukaryotic thermosomes.

Protein Data Bank model 1a6d.