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Recent Citations

Cryo-EM structure of the Rhodospirillum rubrum RC-LH1 complex at 2.5 Å. Qian P, Croll TI et al. Biochem J. 2021 Sep 17;478(17):3253-3263.

Structure of Geobacter pili reveals secretory rather than nanowire behaviour. Gu Y, Srikanth V et al. Nature. 2021 Sep 16;597(7876):430-434.

In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Erdmann PS, Hou Z et al. Nat Commun. 2021 Sep 10;12(1):5364.

Broad betacoronavirus neutralization by a stem helix-specific human antibody. Pinto D, Sauer MM et al. Science. 2021 Sep 3;373(6559):1109-1116.

Evolving cryo-EM structural approaches for GPCR drug discovery. Zhang X, Johnson RM et al. Structure. 2021 Sep 2;29(9):963-974.e6.

(Previously featured citations...)

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News

December 18, 2020

Chimera production release 1.15 is now available. See the release notes for what's new.

December 11, 2020

The RBVI wishes you a safe and happy holiday season! See our 2020 card and the gallery of previous cards back to 1985.

November 4, 2020

A 1.15 production release candidate is available, including a fix to work with the new PDB fetch locations (see the release notes). Please try it and report any problems.

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Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

RR Distance Maps 2gbp and 2fw0

Distance Maps and Contact Maps

RR Distance Maps creates a distance map, a generalization of a protein contact map in which residue-residue distances are shown with color gradations. The map can show the Cα-Cα distances within an individual protein chain or the averages and standard deviations for multiple related chains (as in the figure). A simple binary coloring like a standard contact map can also be obtained.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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