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Balanced plant helper NLR activation by a modified host protein complex. Huang S, Wang J et al. Nature. 2025 Mar 13;639(8054):447–455.
Activation and inhibition mechanisms of a plant helper NLR. Xiao Y, Wu X et al. Nature. 2025 Mar 13;639(8054):438–446.
Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects. Tummino TA, Iliopoulos-Tsoutsouvas C et al. Nat Commun. 2025 Mar 6;16(1):2237.
A widespread plant defense compound disarms bacterial type III injectisome assembly. Miao P, Wang H et al. Science. 2025 Feb 28;387(6737):eads0377.
RNA control of reverse transcription in a diversity-generating retroelement. Handa S, Biswas T et al. Nature. 2025 Feb 27;638(8052):1122–1129.
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March 6, 2025
Chimera production release 1.19 is now available, fixing the ability to fetch structures from the PDB (details...).
December 25, 2024
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October 14, 2024
Planned downtime: The Chimera and ChimeraX websites, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable starting Monday, Oct 14 10 AM PDT, continuing throughout the week and potentially the weekend (Oct 14-20).
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
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Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.
See also the RBVI holiday card gallery.
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