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Recent Citations
Regulation of STING activation by phosphoinositide and cholesterol. Li J, Tan JX et al. Nature. 2026 Apr 9;652(8109):499–507.
Microtubules guide Aurora B substrate geometries for accurate chromosome segregation. Niu Y, DeLuca KF et al. Sci Adv. 2026 Mar 27;12(13):eaea2112.
Discovery and cryoEM structure of FPM13, a periplasmic metalloprotein unique to Francisella. Clemens DL, Lee BY et al. PLoS Pathog. 2026 Mar 27;22(3):e1014024.
LetA defines a structurally distinct transporter family. Santarossa CC, Li Y et al. Nature. 2026 Mar 26;651(8107):1097–1106.
Psychedelics elicit their effects by 5-HT(2A) receptor-mediated G(i) signalling. Xu Z, Wang H et al. Nature. 2026 Mar 19;651(8106):829–837.
Previously featured citations...Chimera Search
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December 25, 2025
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September 22, 2025
Mac users may wish to defer upgrading to MacOS Tahoe. Currently on that OS the Chimera graphics window is shifted so that it covers the command and status lines.
March 6, 2025
Chimera production release 1.19 is now available, fixing the ability to fetch structures from the PDB (1.19 release notes).
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
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The PipesAndPlanks tool shows protein helices as “pipes” (cylinders) and strands as “planks” (rectangular boxes), with connectors for the intervening coil. Adjustable settings include pipe radius, plank width, colors, and whether to include arrowheads to show chain N→C directionality (see image how-to).
(More features...)
Gallery Sample
Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.
See also the RBVI holiday card gallery.
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