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Citations (partial list)

Structural basis for dimerization quality control. Mena EL, Jevtić P et al. Nature. 2020 Oct 15;586(7829):452-456.

Reconstitution and visualization of HIV-1 capsid-dependent replication and integration in vitro. Christensen DE, Ganser-Pornillos BK et al. Science. 2020 Oct 9;370(6513). pii: eabc8420.

Human germinal centres engage memory and naive B cells after influenza vaccination. Turner JS, Zhou JQ et al. Nature. 2020 Oct 1;586(7827):127-132.

CryoEM structure of the tegumented capsid of Epstein-Barr virus. Li Z, Zhang X et al. Cell Res. 2020 Oct;30(10):873-884.

GPSeq reveals the radial organization of chromatin in the cell nucleus. Girelli G, Custodio J et al. Nat Biotechnol. 2020 Oct;38(10):1184-1193.

Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B. Xu TH, Liu M et al. Nature. 2020 Oct 1;586(7827):151-155.

Distinct conformational states of SARS-CoV-2 spike protein. Cai Y, Zhang J et al. Science. 2020 Sep 25;369(6511):1586-1592.

Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Bilokapic S, Suskiewicz MJ et al. Nature. 2020 Sep 24;585(7826):609-613.

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Lv Z, Deng YQ et al. Science. 2020 Sep 18;369(6510):1505-1509.

Amoeboid swimming is propelled by molecular paddling in lymphocytes. Aoun L, Farutin A et al. Biophys J. 2020 Sep 15;119(6):1157-1177.

A molecular pore spans the double membrane of the coronavirus replication organelle. Wolff G, Limpens RWAL et al. Science. 2020 Sep 11;369(6509):1395-1398.

Structural basis of transcription-translation coupling. Wang C, Molodtsov V et al. Science. 2020 Sep 11;369(6509):1359-1365.

Shared structural mechanisms of general anaesthetics and benzodiazepines. Kim JJ, Gharpure A et al. Nature. 2020 Sep 10;585(7824):303–308.

Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Su MY, Fromm SA et al. Nature. 2020 Sep 10;585(7824):251–255.

Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Zhao J, Lin King JV et al. Nature. 2020 Sep 3;585(7823):141-145.

Architecture of a catalytically active homotrimeric plant cellulose synthase complex. Purushotham P, Ho R, Zimmer J. Science. 2020 Aug 28;369(6507):1089-1094.

Architecture and function of human uromodulin filaments in urinary tract infections. Weiss GL, Stanisich JJ et al. Science. 2020 Aug 21;369(6506):1005-1010.

Potently neutralizing and protective human antibodies against SARS-CoV-2. Zost SJ, Gilchuk P et al. Nature. 2020 Aug 20;584(7821):443-449.

Convergent antibody responses to SARS-CoV-2 in convalescent individuals. Robbiani DF, Gaebler C et al. Nature. 2020 Aug 20;584(7821):437-442.

Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies. Barnes CO, West AP Jr et al. Cell. 2020 Aug 20;182(4):828-842.e16.

Structures of metabotropic GABAB receptor. Papasergi-Scott MM, Robertson MJ et al. Nature. 2020 Aug 13;584(7820):310-314.

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability. Brouwer PJM, Caniels TG et al. Science. 2020 Aug 7;369(6504):643-650.

Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane. Yin J, Chen KM et al. Nature. 2020 Aug 6;584(7819):125–129.

Structure of replicating SARS-CoV-2 polymerase. Hillen HS, Kokic G et al. Nature. 2020 Aug 6;584(7819):154-156.

Mycobacterial and human nitrobindins: structure and function. De Simone G, di Masi A et al. Antioxid Redox Signal. 2020 Aug 1;33(4):229-246.

DNA capture by a CRISPR-Cas9-guided adenine base editor. Lapinaite A, Knott GJ et al. Science. 2020 Jul 31;369(6503):566-571.

Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping. Sas-Chen A, Thomas JM et al. Nature. 2020 Jul 23;583(7817):638-643.

Structure of a nascent membrane protein as it folds on the BAM complex. Tomasek D, Rawson S et al. Nature. 2020 Jul 16;583(7816):473-478.

Molecular architecture of the human 17S U2 snRNP. Zhang Z, Will CL et al. Nature. 2020 Jul 9;583(7815):310-313.

Protein Structure Modeling from Cryo-EM Map Using MAINMAST and MAINMAST-GUI Plugin. Terashi G, Zha Y, Kihara D. Methods Mol Biol. 2020 Jul 4;2165:317-336.

Structural insight into mitochondrial β-barrel outer membrane protein biogenesis. Diederichs KA, Ni X et al. Nat Commun. 2020 Jul 3;11(1):3290.

Structural transitions in influenza haemagglutinin at membrane fusion pH. Benton DJ, Gamblin SJ et al. Nature. 2020 Jul 2;583(7814):150-153.

Cryo-EM structures of inactive and active GABAB receptor. Mao C, Shen C et al. Cell Res. 2020 Jul;30(7):564-573.

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Yin W, Mao C et al. Science. 2020 Jun 26;368(6498):1499-1504.

Mass-resolved electronic circular dichroism ion spectroscopy. Daly S, Rosu F, Gabelica V. Science. 2020 Jun 26;368(6498):1465-1468.

A variant in IL6ST with a selective IL-11 signaling defect in human and mouse. Schwerd T, Krause F et al. Bone Res. 2020 Jun 11;8:24.

The structure of human CST reveals a decameric assembly bound to telomeric DNA. Lim CJ, Barbour AT et al. Science. 2020 Jun 5;368(6495):1081-1085.

LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. von Appen A, LaJoie D et al. Nature. 2020 Jun 4;582(7810):115-118.

Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment. Du D, Neuberger A et al. Structure. 2020 Jun 2;28(6):625-634.e6.

Structure of nevanimibe-bound tetrameric human ACAT1. Long T, Sun Y et al. Nature. 2020 May 21;581(7808):339-343.

Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Sui X, Wang K et al. Nature. 2020 May 21;581(7808):323-328.

Genome organization and interaction with capsid protein in a multipartite RNA virus. Beren C, Cui Y et al. Proc Natl Acad Sci USA. 2020 May 19;117(20):10673-10680.

Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins. Saha P, Shumate JL et al. eLife. 2020 May 15;9. pii: e57089.

Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Gao Y, Yan L et al. Science. 2020 May 15;368(6492):779-782.

Action of a minimal contractile bactericidal nanomachine. Ge P, Scholl D et al. Nature. 2020 Apr 30;580(7805):658-662.

Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Dodonova SO, Zhu F et al. Nature. 2020 Apr 30;580(7805):669-672.

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors. Zhang L, Lin D et al. Science. 2020 Apr 24;368(6489):409-412.

Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding. Yu J, Gimenez LE et al. Science. 2020 Apr 24;368(6489):428-433.

The druggability of solute carriers. Wang WW, Gallo L et al. J Med Chem. 2020 Apr 23;63(8):3834-3867.

The ABC exporter IrtAB imports and reduces mycobacterial siderophores. Arnold FM, Weber MS et al. Nature. 2020 Apr 16;580(7803):413-417.

Integrative modeling of a Sin3/HDAC complex sub-structure. Banks CAS, Zhang Y et al. Cell Rep. 2020 Apr 14;31(2):107516.

Ball-and-chain inactivation in a calcium-gated potassium channel. Fan C, Sukomon N et al. Nature. 2020 Apr 9;580(7802):288-293.

Structural effects and functional implications of phalloidin and jasplakinolide binding to actin filaments. Pospich S, Merino F, Raunser S. Structure. 2020 Apr 7;28(4):437-449.e5.

Structure of KCNH2 cyclic nucleotide-binding homology domain reveals a functionally vital salt-bridge. Ben-Bassat A, Giladi M, Haitin Y. J Gen Physiol. 2020 Apr 6;152(4). pii: e201912505.

Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Mukherjee S, Erramilli SK et al. Nat Commun. 2020 Mar 27;11(1):1598.

Structural basis for how biologic medicines bind their targets in psoriasis therapy. Eldirany SA, Ho M, Bunick CG. Yale J Biol Med. 2020 Mar 27;93(1):19-27.

Structural basis of Gs and Gi recognition by the human glucagon receptor. Qiao A, Han S et al. Science. 2020 Mar 20;367(6484):1346-1352.

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Wrapp D, Wang N et al. Science. 2020 Mar 13;367(6483):1260-1263.

Gene expression and cell identity controlled by anaphase-promoting complex. Oh E, Mark KG et al. Nature. 2020 Mar 5;579(7797):136-140.

Structural basis of ligand recognition and self-activation of orphan GPR52. Lin X, Li M et al. Nature. 2020 Mar 5;579(7797):152-157.

Measurement of atom resolvability in cryo-EM maps with Q-scores. Pintilie G, Zhang K et al. Nat Methods. 2020 Mar;17(3):328-334.

Polymerization in the actin ATPase clan regulates hexokinase activity in yeast. Stoddard PR, Lynch EM et al. Science. 2020 Feb 28;367(6481):1039-1042.

Structural basis for strand transfer inhibitor binding to HIV intasomes. Passos DO, Li M et al. Science. 2020 Feb 14;367(6479):810-814.

Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy. Shahnawaz M, Mukherjee A et al. Nature. 2020 Feb 13;578(7794):273-277.

Structure of an active human histone pre-mRNA 3'-end processing machinery. Sun Y, Zhang Y et al. Science. 2020 Feb 7;367(6478):700-703.

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Dick RA, Xu C et al. PLoS Pathog. 2020 Jan 27;16(1):e1008277.

Volatile and thermally stable polymeric tin trifluoroacetates. Bačić G, Rankine CD et al. Inorg Chem. 2020 Jan 21;59(2):996-1005.

Structural basis of substrate recognition by a polypeptide processing and secretion transporter. Kieuvongngam V, Olinares PDB et al. eLife. 2020 Jan 14;9. pii: e51492.

Direct visualization of degradation microcompartments at the ER membrane. Albert S, Wietrzynski W et al. Proc Natl Acad Sci USA. 2020 Jan 14;117(2):1069-1080.

Structure of the human metapneumovirus polymerase phosphoprotein complex. Pan J, Qian X et al. Nature. 2020 Jan 9;577(7789):275-279.

Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Halpin-Healy TS, Klompe SE et al. Nature. 2020 Jan 9;577(7789):271-274.

HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry. Gourh P, Safran SA et al. Proc Natl Acad Sci USA. 2020 Jan 7;117(1):552-562.

The Dundee Resource for Sequence Analysis and Structure Prediction. MacGowan SA, Madeira F et al. Protein Sci. 2020 Jan;29(1):277-297.

Propagation of holes and electrons in metal-organic frameworks. Kriebel M, Hennemann M et al. J Chem Inf Model. 2019 Dec 23;59(12):5057-5064.

Cryo-EM structures of apo and antagonist-bound human Cav3.1. Zhao Y, Huang G et al. Nature. 2019 Dec 19;576(7787):492-497.

Experimental evidence of solvent-separated ion pairs as metastable states in electrostatic interactions of biological macromolecules. Yu B, Pettitt BM, Iwahara J. J Phys Chem Lett. 2019 Dec 19;10(24):7937-7941.

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT. Kim J, Tan YZ et al. Nature. 2019 Dec 12;576(7786):315-320.

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Steichen JM, Lin YC et al. Science. 2019 Dec 6;366(6470):eaax4380.

Molecular insight into RNA polymerase I promoter recognition and promoter melting. Sadian Y, Baudin F et al. Nat Commun. 2019 Dec 5;10(1):5543.

Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus. Fu G, Zhao L et al. J Cell Biol. 2019 Dec 2;218(12):4236-4251.

Antibodies against Plasmodium falciparum malaria at the molecular level. Julien JP, Wardemann H. Nat Rev Immunol. 2019 Dec;19(12):761-775.

The structure and oxidation of the eye lens chaperone αA-crystallin. Kaiser CJO, Peters C et al. Nat Struct Mol Biol. 2019 Dec;26(12):1141-1150.

Cryo-electron microscopy targets in CASP13: Overview and evaluation of results. Kryshtafovych A, Malhotra S et al. Proteins. 2019 Dec;87(12):1128-1140.

Hierarchical assembly governs TRIM5α recognition of HIV-1 and retroviral capsids. Skorupka KA, Roganowicz MD et al. Sci Adv. 2019 Nov 27;5(11):eaaw3631.

Structure of the native supercoiled flagellar hook as a universal joint. Kato T, Makino F et al. Nat Commun. 2019 Nov 22;10(1):5295.

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Lawrence RE, Fromm SA et al. Science. 2019 Nov 22;366(6468):971-977.

Structure of the mitochondrial import gate reveals distinct preprotein paths. Araiso Y, Tsutsumi A et al. Nature. 2019 Nov 14;575(7782):395-401.

Scaffold subunits support associated subunit assembly in the Chlamydomonas ciliary nexin-dynein regulatory complex. Gui L, Song K et al. Proc Natl Acad Sci USA. 2019 Nov 12;116(46):23152-23162.

Calculation of absolute binding free energies between the hERG channel and structurally diverse drugs. Negami T, Araki M et al. Sci Rep. 2019 Nov 12;9(1):16586.

Drivers of α-sheet formation in transthyretin under amyloidogenic conditions. Childers MC, Daggett V. Biochemistry. 2019 Nov 5;58(44):4408-4423.

Architecture of African swine fever virus and implications for viral assembly. Wang N, Zhao D et al. Science. 2019 Nov 1;366(6465):640-644.

A complete data processing workflow for cryo-ET and subtomogram averaging. Chen M, Bell JM et al. Nat Methods. 2019 Nov;16(11):1161-1168.

Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate. Halfon Y, Jimenez-Fernandez A et al. Proc Natl Acad Sci USA. 2019 Oct 29;116(44):22275-22281.

Structural transitions during the scaffolding-driven assembly of a viral capsid. Ignatiou A, Brasilès S et al. Nat Commun. 2019 Oct 24;10(1):4840.

Exploring the effectiveness of binding free energy calculations. Mondal D, Florian J, Warshel A. J Phys Chem B. 2019 Oct 24;123(42):8910-8915.

Structure and genome ejection mechanism of Staphylococcus aureus phage P68. Hrebík D, Štveráková D et al. Sci Adv. 2019 Oct 16;5(10):eaaw7414.

Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC. Müller AU, Leibundgut M et al. Nat Commun. 2019 Oct 11;10(1):4653.

Structural insights into the mechanism of human soluble guanylate cyclase. Kang Y, Liu R et al. Nature. 2019 Oct 10;574(7777):206-210.

Transferrin receptor binds virus capsid with dynamic motion. Lee H, Callaway HM et al. Proc Natl Acad Sci USA. 2019 Oct 8;116(41):20462-20471.

Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases. Kondo Y, Ognjenović J et al. Science. 2019 Oct 4;366(6461):109-115.


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