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Recent Citations

Structure of the intact ATM/Tel1 kinase. Wang X, Chu H et al. Nat Commun. 2016 May 27;7:11655.

Near-atomic resolution visualization of human transcription promoter opening. He Y, Yan C et al. Nature. 2016 May 19;533(7603):359-65.

Structure of the T4 baseplate and its function in triggering sheath contraction. Taylor NM, Prokhorov NS et al. Nature. 2016 May 19;533(7603):346-52.

Transcription initiation complex structures elucidate DNA opening. Plaschka C, Hantsche M et al. Nature. 2016 May 19;533(7603):353-8.

Crystal structures of apo and liganded 4-oxalocrotonate decarboxylase uncover a structural basis for the metal-assisted decarboxylation of a vinylogous β-keto acid. Guimarães SL, Coitinho JB et al. Biochemistry. 2016 May 10;55(18):2632-45.

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News

April 6, 2016

A production release candidate (v1.11) is available; please try it and report any problems. 64-bit builds are now recommended for all capable platforms, and v1.11 will be the last to support 32-bit builds. See the release notes for what's new.

July 23, 2015

Chimera production release 1.10.2 is now available. Fixes include code signing for Mac OS X installation. The 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.

January 9, 2015

Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera. It is in early development and not yet publicly released, with release anticipated sometime in 2016.

Feature Highlight

gradient background
image background

Special Backgrounds

The background of the Chimera graphics window can be set to a single solid color, a vertical gradient of multiple colors, or an image read from a file. These and related parameters can be controlled with the command background or in the Background section of the preferences.

Gradients may contain any number of colors, and can be shown as discrete bands or interpolated in the RBG or HLS color space; they can be created, previewed, and named using the Palette Editor. Background images can be cropped, stretched, centered, or tiled. Image formats include PNG, TIFF, and JPEG.

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Gallery Sample

Cavity and Tunnel Detection

Side-by-side views of a potassium channel structure (Protein Data Bank entry 1bl8) showing different approaches to cavity detection. On the left are molecular surface patches corresponding to the structure's two largest pockets by MS volume in the Computed Atlas of Surface Topography of proteins (CASTp) database. On the right is a tunnel in blue identified by the MolAxis server. Simple editing converted MolAxis output into a BILD file for display in Chimera. (More samples...)