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Featured Citations

Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Liu W, Cui Y et al. Nat Microbiol. 2020 Oct;5(10):1285-1298.

The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase. McKenna MJ, Sim SI et al. Science. 2020 Sep 25;369(6511). pii: eabc5809.

90S pre-ribosome transformation into the primordial 40S subunit. Cheng J, Lau B et al. Science. 2020 Sep 18;369(6510):1470-1476.

Structure of a human 48S translational initiation complex. Brito Querido J, Sokabe M et al. Science. 2020 Sep 4;369(6508):1220-1227.

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Thoms M, Buschauer R et al. Science. 2020 Sep 4;369(6508):1249-1255.

See also: RCSB PDB Images
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News

September 23, 2020

Mac users: ChimeraX v1.1 does not work on MacOS 11.0 (Big Sur), but this problem has been fixed in the daily build.

September 10, 2020

The ChimeraX 1.1 production release is available. See the change log for what's new.

August 27, 2020

The ChimeraX 1.1 release candidate is available. Please try it and report any issues. See the change log for what's new.

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UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.

Feature Highlight

Stylized Nucleotides

Different representations of nucleotides can be shown with the nucleotides command or Toolbar icons. Options include filled rings, slabs for bases (box, muffler, or ellipsoid shape), bumps on slabs to show base orientation, simple tubes instead of ribose atoms, and continuous or broken ladder rungs. Nucleotide representations can be the same color as the ribbon or a different color, and multiple nucleotide styles can be used within a single structure.

See also: Presets menu

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Example Image

The Human Ribosome

The architecture of the human ribosome has been determined at near-atomic resolution by electron microscopy (Anger et al., Nature 497:80 (2013)). The structure, comprising 82 proteins and five RNA molecules, is shown with shadows cast from all directions to accentuate depth. In the background are schematic representations of contacts between the component molecules.

See the image setup script card.cxc using the 'Tis the Season color palette (credit to MrsP). See also the RBVI holiday card gallery.

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