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Craspase is a CRISPR RNA-guided, RNA-activated protease. Hu C, van Beljouw SPB et al. Science. 2022 Sep 16;377(6612):1278-1285.

Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Ehara H, Kujirai T et al. Science. 2022 Sep 9;377(6611):eabp9466.

Archaic chaperone-usher pili self-secrete into superelastic zigzag springs. Pakharukova N, Malmi H et al. Nature. 2022 Sep 8;609(7926):335-340.

Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Kwon JJ, Hajian B et al. Nature. 2022 Sep 8;609(7926):408-415.

Structure of Tetrahymena telomerase-bound CST with polymerase α-primase. He Y, Song H et al. Nature. 2022 Aug 25;608(7924):813-818.

(Previously featured citations...)

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News

September 27, 2022

Website downtime: The RBVI website (Chimera, ChimeraX, etc.) and RBVI-hosted web services will be down for maintenance from Tue, Sep 27 9pm PDT, through Wed, possibly extending to Thu, Sep 29 5pm PDT.

December 20, 2021

The RBVI wishes you a safe and happy holiday season! See our 2021 card and the gallery of previous cards back to 1985.

December 17, 2021

Chimera production release 1.16 is now available. This will be the last release to support Windows 7. See the release notes for what's new.

(Previous news...)

Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

Volume Data

Volume Data

Chimera's Volume Viewer displays three-dimensional electron and light microscope data, X-ray density maps, electrostatic potential and other volumetric data. Contour surfaces, meshes and volumetric display styles are provided and thresholds can be changed interactively. Maps can be colored, sliced, segmented, and modifications can be saved. Markers can be placed and structures can be traced. The accompanying image shows a density map of Kelp fly virus from electron microscopy colored radially and with an octant cut out.

(More features...)

Gallery Sample

Wasabi Receptor

The image shows the structure of the human TRPA1 ion channel (wasabi receptor) determined by electron cryo-microscopy, Protein Data Bank entry 3j9p. The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background. (More samples...)


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