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Recent Citations

Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Nogly P, Weinert T et al. Science. 2018 Jul 13;361(6398). pii: eaat0094.

Structural analysis of influenza vaccine virus-like particles reveals a multicomponent organization. McCraw DM, Gallagher JR et al. Sci Rep. 2018 Jul 9;8(1):10342.

Repurposing drugs to target the malaria parasite unfolding protein response. Chen Y, Murillo-Solano C et al. Sci Rep. 2018 Jul 9;8(1):10333.

Structure of a human synaptic GABAA receptor. Zhu S, Noviello CM et al. Nature. 2018 Jul 5;559(7712):67-72.

Modeling protein complexes using restraints from crosslinking mass spectrometry. Bullock JMA, Sen N et al. Structure. 2018 Jul 3;26(7):1015-1024.e2.

(Previously featured citations...)

Chimera Search

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News

July 3, 2018

Chimera production release 1.13 is now available. See the release notes for what's new.

June 2, 2018

A production release candidate (version 1.13) is available; please try it and report any problems. See the release notes for what's new.

October 24, 2017

Chimera production release 1.12 is now available (64-bit builds for Windows, Mac, and Linux). See the release notes for details.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

EM map morph

Morphing Density Maps

Related density maps can be compared by morphing from one to the other. Several intermediate maps are generated by interpolating between the starting and ending maps. The morph can be viewed interactively and recorded as a movie. The contour level can be adjusted automatically to keep the enclosed volume constant throughout the morph, and other aspects of map display can be adjusted with Volume Viewer.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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