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Featured Citations
Stereochemistry in the disorder-order continuum of protein interactions. Newcombe EA, Due AD et al. Nature. 2024 Dec 19;636(8043):762–768.
MCM double hexamer loading visualized with human proteins. Weissmann F, Greiwe JF et al. Nature. 2024 Dec 12;636(8042):499–508.
Multiple mechanisms for licensing human replication origins. Yang R, Hunker O et al. Nature. 2024 Dec 12;636(8042):488–498.
Molecular sociology of virus-induced cellular condensates supporting reovirus assembly and replication. Liu X, Xia X et al. Nat Commun. 2024 Dec 6;15(1):10638.
Broadly inhibitory antibodies to severe malaria virulence proteins. Reyes RA, Raghavan SSR et al. Nature. 2024 Dec 5;635(8041):182–189.
More citations...News
December 12, 2024
The ChimeraX 1.9 production release is available! See the change log for what's new.
October 14, 2024
Planned downtime: The ChimeraX website, Toolshed, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable starting Monday, Oct 14 10 AM PDT, continuing throughout the week and potentially the weekend (Oct 14-20).
August 1, 2024
Planned downtime: The ChimeraX website, Toolshed, web services (Blast Protein, Modeller, ...) and cgl.ucsf.edu e-mail will be unavailable August 1, 3-6 pm PDT.
Previous news...Upcoming Events
UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.
ChimeraX is developed with support from National Institutes of Health R01-GM129325, Chan Zuckerberg Initiative grant EOSS4-0000000439, and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.
Feature Highlight
Coulombic electrostatic potential (ESP) can be calculated
and displayed with surface coloring using the command
coulombic
or the
Molecule Display
icon
.
No separate calculation or input ESP file is required.
The image shows the first assembly defined for PDB
3eeb, the protease domain of a toxin from
Vibrio cholerae,
with the default Coulombic coloring: red-white-blue over the value range
–10 to 10. For image setup other than orientation, see the
command file coulombic.cxc.
For how to add a color key and associated label, see the Protein-Ligand Binding Sites tutorial.
More features...Example Image
The photosynthetic reaction center from a
purple sulfur bacterium is shown as a cartoon with “tube” helices
and membrane boundaries from the OPM database (Orientations of Proteins in Membranes,
entry 1eys).
Blue and red balls represent the cytoplasmic and periplasmic sides
of the bacterial inner membrane, respectively.
The title and other text labels were added with the
2dlabels
command and repositioned interactively with the move label
mouse mode
.
ChimeraX session file: prc.cxs
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